“Organ Failure” is a four-panel meme about human organs. Each panel shows a different organ, with the final panel showing the brain. The meme is often used to humorously illustrate the consequences of neglecting brain health.
The artist Stonetoss first put this meme online in the form of a webcomic. It came out for the first time on December 20, 2022, and after a while, it started to get popular on Reddit and other social platforms.
The meme makes use of dark humor to bring attention to the significance of maintaining good mental health and how this can have an effect on an individual's overall well-being. It is a useful prompt to keep in mind the importance of giving equal weight to the maintenance of one's mental health as one does to one's physical health.